Surface antigens of melanocytes and melanomas. Markers of melanocyte differentiation and melanoma subsets
نویسندگان
چکیده
The surface antigens of melanocytes from newborn and adult skin have been analyzed with monoclonal antibodies detecting cell surface antigens of malignant melanoma. Antigenic markers that distinguish early, intermediate, and mature stages in melanocyte differentiation have been defined. The characteristics of the normal melanocyte precursor have been inferred from the features of melanomas that express early markers of melanocyte differentiation. A rudimentary surface antigen map of cells undergoing melanocyte differentiation and a new classification of melanomas based on the expression of melanocyte differentiation antigens are proposed.
منابع مشابه
Cell Surface Antigens of Human Melanocytes and Melanoma
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ورودعنوان ژورنال:
- The Journal of Experimental Medicine
دوره 156 شماره
صفحات -
تاریخ انتشار 1982